The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection. Richards CM, Jabs S, Qiao W, Varanese LD, Schweizer M, Mosen PR, Riley NM, Klüssendorf M, Zengel JR, Flynn RA, Rustagi A, Widen JC, Peters CE, Ooi YS, X

The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection.

Richards CM, Jabs S, Qiao W, Varanese LD, Schweizer M, Mosen PR, Riley NM, Klüssendorf M, Zengel JR, Flynn RA, Rustagi A, Widen JC, Peters CE, Ooi YS, Xie X, Shi PY, Bartenschlager R, Puschnik AS, Bogyo M, Bertozzi CR, Blish CA, Winter D, Nagamine CM, Braulke T, Carette JE.

Science, October 2022

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An atlas of posttranslational modifications on RNA binding proteins. England WE, Wang J, Chen S, Baldi P, Flynn RA, Spitale RC. Nucleic Acids Research, May 2022 Pubmed PDF

An atlas of posttranslational modifications on RNA binding proteins.

England WE, Wang J, Chen S, Baldi P, Flynn RA, Spitale RC.

Nucleic Acids Research, May 2022

Pubmed PDF

The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C. Pluvinage JV, Sun J, Claes C, Flynn RA, Haney MS, Iram T, Meng X, Lindemann R, Riley NM, Danhash E, Chadarevian JP, Tapp E, Gate D, Ko

The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C.

Pluvinage JV, Sun J, Claes C, Flynn RA, Haney MS, Iram T, Meng X, Lindemann R, Riley NM, Danhash E, Chadarevian JP, Tapp E, Gate D, Kondapavulur S, Cobos I, Chetty S, Pașca AM, Pașca SP, Berry-Kravis E, Bertozzi CR, Blurton-Jones M, Wyss-Coray T

Science Translational Medicine, December 2021

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Diverse functional elements in RNA predicted transcriptome-wide by orthogonal RNA structure probing. Chan D*, Feng C*, England WE*, Wyman D, Flynn RA, Wang X, Shi Y, Mortazavi A, Spitale RC Nucleic Acids Research , October 2021 Pubmed P

Diverse functional elements in RNA predicted transcriptome-wide by orthogonal RNA structure probing.

Chan D*, Feng C*, England WE*, Wyman D, Flynn RA, Wang X, Shi Y, Mortazavi A, Spitale RC

Nucleic Acids Research, October 2021

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fSHAPE, fSHAPE-eCLIP, and SHAPE-eCLIP probe transcript regions that interact with specific proteins Corley M, Flynn RA, Blue SM, Yee BA, Chang HY, Yeo GW STAR Protocols , September 2021 Pubmed PDF

fSHAPE, fSHAPE-eCLIP, and SHAPE-eCLIP probe transcript regions that interact with specific proteins

Corley M, Flynn RA, Blue SM, Yee BA, Chang HY, Yeo GW

STAR Protocols, September 2021

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Small RNAs are modified with N-glycans and displayed on the surface of living cells. Flynn RA#, Pedram K, Malaker SA, Batista PJ, Smith BAH, Johnson AG, George BM, Majzoub K, Villalta PW, Carette JE, Bertozzi CR#. # co-corresponding Cell , Ju

Small RNAs are modified with N-glycans and displayed on the surface of living cells.

Flynn RA#, Pedram K, Malaker SA, Batista PJ, Smith BAH, Johnson AG, George BM, Majzoub K, Villalta PW, Carette JE, Bertozzi CR#. # co-corresponding

Cell, June 2021

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Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions. Flynn RA#,* Belk JA, Qi Y, Yasumoto Y, Wei J, Alfajaro MM, Shi Q, Mumbach MR, Limaye A, DeWeirdt PC, Schmitz CO, Parker KR, Woo E, Chang HY, Horvath TL, Carette

Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions.

Flynn RA#,* Belk JA, Qi Y, Yasumoto Y, Wei J, Alfajaro MM, Shi Q, Mumbach MR, Limaye A, DeWeirdt PC, Schmitz CO, Parker KR, Woo E, Chang HY, Horvath TL, Carette JE, Bertozzi CR, Wilen CB#, Satpathy AT#. * equal contribution, # co-corresponding

Cell, April 2021

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The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection. Richards CM, Jabs S, Qiao W, Varanese LD, Schweizer M, Mosen PR, Riley NM, Klüssendorf M, Zengel JR, Flynn RA, Rustagi A, Widen JC, Peters CE, Ooi YS, X
An atlas of posttranslational modifications on RNA binding proteins. England WE, Wang J, Chen S, Baldi P, Flynn RA, Spitale RC. Nucleic Acids Research, May 2022 Pubmed PDF
The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C. Pluvinage JV, Sun J, Claes C, Flynn RA, Haney MS, Iram T, Meng X, Lindemann R, Riley NM, Danhash E, Chadarevian JP, Tapp E, Gate D, Ko
Diverse functional elements in RNA predicted transcriptome-wide by orthogonal RNA structure probing. Chan D*, Feng C*, England WE*, Wyman D, Flynn RA, Wang X, Shi Y, Mortazavi A, Spitale RC Nucleic Acids Research , October 2021 Pubmed P
fSHAPE, fSHAPE-eCLIP, and SHAPE-eCLIP probe transcript regions that interact with specific proteins Corley M, Flynn RA, Blue SM, Yee BA, Chang HY, Yeo GW STAR Protocols , September 2021 Pubmed PDF
Small RNAs are modified with N-glycans and displayed on the surface of living cells. Flynn RA#, Pedram K, Malaker SA, Batista PJ, Smith BAH, Johnson AG, George BM, Majzoub K, Villalta PW, Carette JE, Bertozzi CR#. # co-corresponding Cell , Ju
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions. Flynn RA#,* Belk JA, Qi Y, Yasumoto Y, Wei J, Alfajaro MM, Shi Q, Mumbach MR, Limaye A, DeWeirdt PC, Schmitz CO, Parker KR, Woo E, Chang HY, Horvath TL, Carette