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Flynn Lab

Research
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  Flynn RA *, Almada AE*, Zamudio JR, Sharp PA.   Antisense RNA polymerase II divergent transcripts are P-TEFb dependent substrates for the RNA exosome.    PNAS . July 2011   Pubmed       PDF

Flynn RA*, Almada AE*, Zamudio JR, Sharp PA.

Antisense RNA polymerase II divergent transcripts are P-TEFb dependent substrates for the RNA exosome.

PNAS. July 2011

Pubmed     PDF

 Huang PH, Miraldi ER, Xu AM, Kundukulam VA, Del Rosario AM,  Flynn RA , Cavenee WK, Furnari FB, White FM.  Phosphotyrosine signaling analysis of site-specific mutations on EGFRvIII identifies determinants governing glioblastoma cell growth.   Mol Bi

Huang PH, Miraldi ER, Xu AM, Kundukulam VA, Del Rosario AM, Flynn RA, Cavenee WK, Furnari FB, White FM.

Phosphotyrosine signaling analysis of site-specific mutations on EGFRvIII identifies determinants governing glioblastoma cell growth.

Mol Biosystems. May 2010

Pubmed     PDF

 Rahl PB, Lin CY, Seila AC,  Flynn RA , McCuine S, Burge CB, Sharp PA, Young RA.   c-Myc regulates transcriptional pause release.    Cell . April 2010   Pubmed       PDF

Rahl PB, Lin CY, Seila AC, Flynn RA, McCuine S, Burge CB, Sharp PA, Young RA.

c-Myc regulates transcriptional pause release.

Cell. April 2010

Pubmed     PDF

 Seila AC, Calabrese M, Levine SS, Yeo GW, Rahl PB,  Flynn RA , Young RA, Sharp PA.   Divergent transcription from active promoters.    Science . December 2008   Pubmed       PDF    

Seila AC, Calabrese M, Levine SS, Yeo GW, Rahl PB, Flynn RA, Young RA, Sharp PA.

Divergent transcription from active promoters.

Science. December 2008

Pubmed     PDF

 

 Huang PH, Mukasa A, Bonavia R,  Flynn RA , Brewer ZE, Cavenee WK, Furnari FB, White FM.   Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma.    PNAS . July 2007   Pubmed  &nbs

Huang PH, Mukasa A, Bonavia R, Flynn RA, Brewer ZE, Cavenee WK, Furnari FB, White FM.

Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma.

PNAS. July 2007

Pubmed     PDF

 Tuli R,  Flynn RA , Brill KL, Sabol JL, Usuki KY, Rosenberg AL.    Diagnosis, treatment, and management of breast cancer in previously augmented women.    Breast J . August 2006   Pubmed       PDF

Tuli R, Flynn RA, Brill KL, Sabol JL, Usuki KY, Rosenberg AL. 

Diagnosis, treatment, and management of breast cancer in previously augmented women.

Breast J. August 2006

Pubmed     PDF

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  Flynn RA *, Almada AE*, Zamudio JR, Sharp PA.   Antisense RNA polymerase II divergent transcripts are P-TEFb dependent substrates for the RNA exosome.    PNAS . July 2011   Pubmed       PDF
 Huang PH, Miraldi ER, Xu AM, Kundukulam VA, Del Rosario AM,  Flynn RA , Cavenee WK, Furnari FB, White FM.  Phosphotyrosine signaling analysis of site-specific mutations on EGFRvIII identifies determinants governing glioblastoma cell growth.   Mol Bi
 Rahl PB, Lin CY, Seila AC,  Flynn RA , McCuine S, Burge CB, Sharp PA, Young RA.   c-Myc regulates transcriptional pause release.    Cell . April 2010   Pubmed       PDF
 Seila AC, Calabrese M, Levine SS, Yeo GW, Rahl PB,  Flynn RA , Young RA, Sharp PA.   Divergent transcription from active promoters.    Science . December 2008   Pubmed       PDF    
 Huang PH, Mukasa A, Bonavia R,  Flynn RA , Brewer ZE, Cavenee WK, Furnari FB, White FM.   Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma.    PNAS . July 2007   Pubmed  &nbs
 Tuli R,  Flynn RA , Brill KL, Sabol JL, Usuki KY, Rosenberg AL.    Diagnosis, treatment, and management of breast cancer in previously augmented women.    Breast J . August 2006   Pubmed       PDF
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The scientist does not study nature because it is useful; they study it because they delight in it, and they delight in it because it is beautiful. If nature were not beautiful, it would not be worth knowing, and if nature were not worth knowing , life would not be worth living.
-Henri Poincare