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Flynn Lab

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Featured
  RNA Crossing Membranes: Systems and Mechanisms Contextualizing Extracellular RNA and Cell Surface GlycoRNAs.   Chai P, Lebedenko CG, Flynn RA#.   Annu Rev Genomics Hum Genetics , April 2023   Pubmed       PDF
Apr 20, 2023
Apr 20, 2023

RNA Crossing Membranes: Systems and Mechanisms Contextualizing Extracellular RNA and Cell Surface GlycoRNAs.

Chai P, Lebedenko CG, Flynn RA#.

Annu Rev Genomics Hum Genetics, April 2023

Pubmed PDF

Apr 20, 2023
  LINE-associated cryptic splicing induces dsRNA-mediated interferon response and tumor immunity.   Zheng R, Dunlap M, Lyu J, Gonzalez-Figueroa C, Bobkov G, Harvey SE, Chan TW, Quinones-Valdez G, Choudhury M, Vuong A, Flynn RA, Chang HY, Xiao X, Chen
Apr 20, 2023
Apr 20, 2023

LINE-associated cryptic splicing induces dsRNA-mediated interferon response and tumor immunity.

Zheng R, Dunlap M, Lyu J, Gonzalez-Figueroa C, Bobkov G, Harvey SE, Chan TW, Quinones-Valdez G, Choudhury M, Vuong A, Flynn RA, Chang HY, Xiao X, Cheng C.

bioRxiv, February 2023

Pubmed

Apr 20, 2023
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Apr 20, 2023
Apr 20, 2023
Apr 20, 2023
  A (cross)link in the chains.   Watkins CP, Flynn RA#.   Nature Chemistry , January 2023   Pubmed       PDF
Apr 20, 2023
Apr 20, 2023

A (cross)link in the chains.

Watkins CP, Flynn RA#.

Nature Chemistry, January 2023

Pubmed PDF

Apr 20, 2023
  Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation.    Miao W, Porter DF, Lopez-Pajares V, Siprashvili Z, Meyers RM, Bai Y, Nguyen DT, Ko LA, Zarnegar BJ, Ferguson ID, Mills MM, Jilly-Rehak CE, Wu CG, Yang YY, Mey
Apr 20, 2023
Apr 20, 2023

Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation.

Miao W, Porter DF, Lopez-Pajares V, Siprashvili Z, Meyers RM, Bai Y, Nguyen DT, Ko LA, Zarnegar BJ, Ferguson ID, Mills MM, Jilly-Rehak CE, Wu CG, Yang YY, Meyers JM, Hong AW, Reynolds DL, Ramanathan M, Tao S, Jiang S, Flynn RA, Wang Y, Nolan GP, Khavari PA.

Cell, January 2023

Pubmed PDF

Apr 20, 2023
  Nuclear accumulation of host transcripts during Zika Virus Infection.   Leon KE, Khalid MM, Flynn RA, Fontaine KA, Nguyen TT, Kumar GR, Simoneau CR, Tomar S, Jimenez-Morales D, Dunlap M, Kaye J, Shah PS, Finkbeiner S, Krogan NJ, Bertozzi C, Carette
Apr 20, 2023
Apr 20, 2023

Nuclear accumulation of host transcripts during Zika Virus Infection.

Leon KE, Khalid MM, Flynn RA, Fontaine KA, Nguyen TT, Kumar GR, Simoneau CR, Tomar S, Jimenez-Morales D, Dunlap M, Kaye J, Shah PS, Finkbeiner S, Krogan NJ, Bertozzi C, Carette JE, Ott M.

PLoS Pathog, January 2023

Pubmed PDF

Apr 20, 2023
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The scientist does not study nature because it is useful; they study it because they delight in it, and they delight in it because it is beautiful. If nature were not beautiful, it would not be worth knowing, and if nature were not worth knowing , life would not be worth living.
-Henri Poincare